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个性化时调节的5-甲治疗:一种基于生理学的药理动力学精确剂量方法,用于优化癌症治疗

Fatima Zahra Marok1, Jan-Georg Wojtyniak1,2, Dominik Selzer1

  • 1Clinical Pharmacy, Saarland University, Saarbruecken, Germany.

Clinical pharmacology and therapeutics
|January 24, 2024
PubMed
概括

这项研究模拟了5-fluorouracil (5-FU) 代谢,以个性化癌症治疗. 它估计了个体的二皮里米丁脱酶 (DPD) 时型,以优化时调制的5-FU剂量,以获得更好的患者结果.

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