通过免疫检查点抑制剂疗法诱导的类固醇依赖性多关节炎成功地用比梅奇祖马布治疗
Robin Springer1, Kristin Lange1, Bernhard Homey1
1Department of Dermatology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Immunotherapy
|January 24, 2024
概括
免疫检查点抑制剂 (ICI) 可以导致严重的多关节炎. 一位对类固醇无反应的患者通过IL-17抑制剂比梅奇祖马布获得完全缓解,为这种罕见的免疫相关不良事件提供了新的治疗选择.
科学领域:
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 免疫检查点抑制剂 (ICI) 在癌症治疗中至关重要,但可以引发与免疫相关的不良事件 (irAEs).
- 肌肉骨性情形,包括多关节炎,不太常见,但不太了解.
- 目前除了葡萄糖皮质类固醇之外的管理指南是有限的.
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