孕前血压和不良妊娠结果:基于人口的队列研究
Wenxue Xiong1, Lu Han2, Xijia Tang1
1Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China (W.X., X.T., W.C., R.L., L.L.).
Hypertension (Dallas, Tex. : 1979)
|January 24, 2024
概括
在怀孕前血压升高和高血压增加了不良妊娠结果 (APO) 的风险. 然而,如果女性准备怀孕超过90天,这种风险会显著降低.
科学领域:
- 产科和妇科 产科和妇科
- 心血管疾病研究研究
- 公共卫生 公共卫生
背景情况:
- 负面的妊娠结果 (APO) 与心血管疾病的风险因素是相同的.
- 在生育年龄的女性中,高血压的患病率正在上升.
- 孕前血压和APO之间的联系尚未得到充分证实.
研究的目的:
- 调查孕前母亲血压水平与不良妊娠结果之间的关联.
- 在怀孕前患有高血压或高血压的女性中量化APO风险.
主要方法:
- 一项基于人口的队列研究,对567,127个母亲-新生儿-父亲三位一体进行了研究.
- 使用美国妇产科医生学院的高血压定义分类的孕产妇血压.
- 逻辑双项和边际结构双项回归用于分析复合APOs (早产,对于妊娠年龄来说很小,围产死亡).
主要成果:
- 与血压正常的女性相比,患有高血压或高血压的女性患复合APO的风险明显更高.
- 特定的APO包括早产,对于妊娠年龄来说小,以及围产婴儿死亡,在高血压或高血压的妇女中也更为频繁.
- 对于那些准备怀孕超过90天的女性来说,这些关联在统计学上并不显著.
结论:
- 在怀孕前血压升高和高血压与怀孕不良结果的风险增加有关.
- 孕前查和高血压的管理对于母亲和婴儿的健康至关重要.
- 较长的怀孕准备期可能会减轻与妊娠前血压升高相关的风险.
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