根据世界卫生组织2022年第5次分类,重新分类乳头,瘤和染色体性瘤
1Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, KARNATAKA, INDIA.
Turk patoloji dergisi
|January 24, 2024
概括
世界卫生组织第五次分类引入了新的分子脏瘤,影响了 papillary, oncocytic 和 chromophobe 瘤诊断. 病理学家在低资源环境中面临挑战,因为需要先进的分子测试.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 遗传学 是一个遗传学.
背景情况:
- 世界卫生组织 (WHO) 关于瘤的第五次分类引入了新的分子实体.
- 主要更新包括删除乳头脏细胞癌 (PRCC) 的亚型.
- 新兴实体需要在诊断细胞和染色恐惧性瘤时加以考虑.
研究的目的:
- 根据世界卫生组织第五种分类来审查和重新分类瘤.
- 将新的分类与临床,粗体,显微和免疫组织化学发现相关联.
- 评估新分类对诊断准确性的影响.
主要方法:
- 对13例脏瘤病例的回顾性审查.
- 根据世卫组织第五项分类标准进行重新分类.
- 与临床数据,组织病理学和免疫组织化学的相关性.
主要成果:
- 在4例状脏细胞癌病例中的3例中,瘤等级发生了改变.
- 一例状细胞癌的病例被重新分类和分级.
- 在9例瘤细胞和染色恐惧性脏瘤病例中的3例中,诊断得到了修改.
结论:
- 新的分子瘤需要先进的免疫组织化学和分子测试.
- 在缺乏分子测试能力的低资源环境中,病理学家面临的诊断挑战.
- 瘤分类的不断变化的格局需要对诊断方法进行调整.
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