味道塑造了植物药物的使用
Marco Leonti1, Joanna Baker2, Peter Staub1
1Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
eLife
|January 24, 2024
概括
化学感觉,味道和风味的感知,强烈预测古代药物使用. 具有多功能治疗应用的植物药物通常具有简单,强烈的味道和风味,影响了它们的历史医学应用.
科学领域:
- 民族植物学 民族植物学
- 化学感应是一种化学感应.
- 药理学 药理学是指药理学的学科.
背景情况:
- 化学感知 (味觉,嗅觉,化解) 对于识别食物和避免毒素至关重要.
- 人类使用植物物质作为药物的化学传感作用尚不清楚.
- 古希腊罗马医学常常将疾病归因于幽默失衡.
研究的目的:
- 研究植物药物的化学传感特性是否预测了它们的古老治疗用途.
- 分析味道,味道复杂性,强度和药用多功能性之间的关系.
主要方法:
- 收集了植物药物的品尝面板数据.
- 应用了遗传学概括的线性混合模型.
- 与古希腊罗马药物使用模式相关联的化学感知特征.
主要成果:
- 化学感知特性对治疗应用具有很高的预测性.
- 具有广泛治疗用途的植物药物表现出简单而又强烈的味道和风味.
- 特定的口味/味道 (苦味,粉,香,甜味,肥) 与药物的多功能性有关.
结论:
- 古老的药物使用是由可观察到的生理效应告知的,与现代的化学感知科学保持一致.
- 化学感应在药用植物的历史选择和应用中起着重要作用.
- 这些发现挑战了纯粹幽默的理论,并提出了经验,感官驱动的观测的基础.
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