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测量体质组织中大量和单细胞分辨率的遗传多样化

Marius E Moeller1, Nathaniel V Mon Père2,3, Benjamin Werner2

  • 1Department of Mathematics, Queen Mary University of London, London, United Kingdom.

eLife
|January 24, 2024
PubMed
概括

组织中的遗传异质性源于体质突变. 新的测序方法揭示了干细胞动态和突变率,揭示了超出简单模型的额外随机性.

关键词:
进化生物学是进化的生物学.进化推断的演化推断.健康的人体组织健康的人体组织.人类 人类 人类 人类 人类 人类 人类采样采样 采样采样单细胞突变负担是很大的.干细胞的动态 干细胞的动态变异的等位基因频率变异

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