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失去戈尔吉局部化的v-ATPase亚单元不会改变胰岛素颗粒的形成或胰腺小岛β细胞的功能

Cierra K Boyer1,2, Sandra E Blom2,3, Ashleigh E Machado2,3

  • 1Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa, United States.

American journal of physiology. Endocrinology and metabolism
|January 24, 2024
PubMed
概括

改变β细胞中的戈尔吉 pH 会影响2型糖尿病中胰岛素颗粒的形成. 虽然v0a2淘汰赛部分中和了戈尔吉的pH值,但它不会影响亲胰岛素出口或葡萄糖恒温.

关键词:
这就是RUSH的冲动.胰岛素分泌的胰岛素分泌.有机细胞的pH值亲胰岛素的非法贩运.这是一个v-ATPasease.

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