哺乳动物STE20样酶1通过SIRT3/mTOR轴介导的线粒体功能障碍抑制了类风湿性关节炎中同胞细胞的激活

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Min Tan1,2, Jing Mao1,2, Jianxiong Zheng1,2

  • 1Department of Rheumatology, Lanzhou University Second Hospital, No. 82, Cui Ying Men Street, Lanzhou City, 730030, Gansu Province, People's Republic of China.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
|January 24, 2024
PubMed
概括

哺乳动物STE20样酶1 (MST1) 在类风湿性关节炎 (RA) 中是下调的. 抑制MST1抑制RA纤维细胞样同胞细胞,通过影响线粒体功能来减少炎症和骨质侵蚀.

关键词:
纤维细胞类同胞细胞类似于纤维细胞.哺乳动物STE20类激酶1线粒体功能障碍 线粒体功能障碍类风湿性关节炎 类风湿性关节炎 类风湿性关节炎在SIRT3/mTOR轴上.

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