对于食道状细胞癌的非治愈性内镜切除后的长期结果,其次是额外的化学放射治疗
Hourin Cho1, Seiichiro Abe1, Satoru Nonaka1
1Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
概括
对于以非治愈性内镜切除 (ER) 和化疗放射治疗 (CRT) 治疗的食道状细胞癌 (ESCC),淋巴侵袭是复发的关键风险因素. 对这些患者来说,长期跟踪对这些患者至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 对于食道状细胞癌 (ESCC) 的非治愈性内镜切除 (ER) 需要进一步治疗.
- 化学辐射疗法 (CRT) 是ESCC非治愈性ER后的常见附加治疗.
研究的目的:
- 为了评估ESCC患者的长期结果,他们接受了非治愈性ER治疗,随后进行CRT.
- 在这个患者队列中确定复发的风险因素.
主要方法:
- 对97名ESCC非治愈性ER患者的回顾性审查,其中73人接受了额外的CRT.
- 对复发率,生存率和风险因素的分析,包括淋巴侵袭和淋巴结转移.
主要成果:
- 在14%的患者 (10/73) 观察到复发,随访时间中位数为71个月.
- 三年和五年无复发生存率分别为89%和85%.
- 淋巴侵袭被确定为复发的独立风险因素.
结论:
- 淋巴侵袭是ESCC患者复发的重要预测因素,这些患者接受了非治愈的ER和CRT.
- 用ER和CRT治疗的非治愈性ESCC患者需要在治疗后至少5年进行仔细的长期监测.
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