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Updated: Jul 5, 2025

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在转位细胞癌中,TFE3-剪接因子融合代表了功能驱动因素和可药物接的标

Nur P Damayanti1,2,3, Ricardo A Cordova3,4, Christopher Rupert5

  • 1Genitourinary Program, Division of Hematology & Oncology, Indiana University, Indianapolis, Indiana.

Cancer research
|January 24, 2024
PubMed
概括

向TFE3拼接因子 (TFE3-SF) 融合,这是转位细胞癌 (tRCC) 中常见的,提供了一个新的治疗策略. 抑制TFE3-SF二分化抑制了瘤生长,而terfenadine在临床前模型中显示出有前途.

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