功能性便秘引起的口外口臭的特征:一个前性队列研究
Xiao Xian Qian1,2,3
1Department of Gastroenterology, Minhang Hospital, Fudan University, Shanghai 201199, People's Republic of China.
Journal of breath research
|January 24, 2024
概括
功能性便秘 (FC) 经常导致口外口臭,主要是由二甲基硫化物 (DMS) 驱动的. 目前的诊断值不够,需要进行调整,以使用Halimeter和OralChroma设备进行准确的检测.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生物化学 生物化学
背景情况:
- 与功能性便秘 (FC) 相关的口腔外口臭仍然不太了解.
- 以前的口臭诊断标准可能无法有效识别与FC相关的病例.
研究的目的:
- 为了表征非口腔口臭在FC患者.
- 评估当前诊断工具的有效性,并提出调整的值.
主要方法:
- 一项前性队列研究涉及100名FC患者,分为口臭和负组.
- 在呼吸中测量挥发性硫化合物 (VSCs) 使用海利米特和OralChroma,并进行感官评分 (OLS).
主要成果:
- 82%的FC患者表现出口腔外口臭,通常不被现有的值检测到.
- 硫化二甲基 (DMS) 被确定为主要的VSC贡献者.
- 在OLS,VSC和总VSC (C-sum) 之间发现了显著的相关性.
结论:
- 硫化二甲基 (DMS) 是导致FC引起的口腔外口臭的主要原因.
- 器官感官评分 (OLS),度仪和OralChroma在检测方面是一致的.
- 建议调整的诊断值:C-VSC ≥36个ppb和C-DMS ≥52个ppb.
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