严重的空气污染,较差的认知功能:来自中国西北部176,345名长老的调查结果
Zhaohuan Gui1, Weidong Ji2, Yushan Wang3
1Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Ecotoxicology and environmental safety
|January 24, 2024
概括
长期暴露于PM2.5,PM10和臭氧等空气污染物与老年人认知功能不佳有关. 减少空气污染可能有助于改善老年人的认知健康.
科学领域:
- 环境健康 环境健康
- 老年学是一门学科.
- 流行病学 流行病学
背景情况:
- 关于空气污染对发展中国家认知功能影响的研究有限.
- 在某些地区,自然颗粒物来源普遍存在,使暴露评估复杂化.
研究的目的:
- 为了检查空气污染与中国西北部大量老年人口的认知功能之间的关联.
- 评估细颗粒物 (PM2.5,PM10) 和气体污染物 (SO2,NO2,CO,O3) 对认知健康的影响.
主要方法:
- 在中国 (2020年) 对176,345名60-100岁的个体进行横截面研究.
- 基于卫星的建模估计了年度平均污染物度 (PM2.5,PM10,SO2,NO2,CO,O3).
- 通过迷你心理状态检查 (MMSE) 评估认知功能;使用通用线性混合模型进行统计分析.
主要成果:
- 对PM2.5,PM10和臭氧的更高暴露与认知功能低下和MMSE得分较低的可能性增加相关.
- 在PM2.5,PM10和O3中增加10μg/m3对应于分别为1.26,1.06和2.76的不良认知功能的几率比率.
- 在年轻,非维吾尔族和身体活跃的参与者中观察到更强烈的关联.
结论:
- 长期暴露于PM2.5,PM10和臭氧与老年人的认知功能受损有显著的关联.
- 研究结果表明,减少空气污染的战略可以减轻老年人群认知能力下降的负担.
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