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在哺乳动物的发育过程中,昼夜钟振荡的出现

Kazuhiro Yagita1

  • 1Department of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Current opinion in genetics & development
|January 24, 2024
PubMed
概括

哺乳动物的胚胎发育涉及到昼夜钟的出现,这是内部的生物节奏. 这些时钟与细胞分化有关,在初始的超日节律之后发展,由分段时钟控制.

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Circadian Rhythms and Gene Regulation02:19

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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