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Updated: Jul 5, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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干白素21驱动超代谢状态和CD4+T细胞相关的致病性在慢性肠道炎症

Adebowale O Bamidele1, Shravan K Mishra2, Guilherme Piovezani Ramos3

  • 1Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; Department of Immunology, Mayo Clinic, Rochester, Minnesota.

Gastroenterology
|January 24, 2024
PubMed
概括

干白素-21 (IL21) 损害了调节性T细胞 (Treg) 代谢,促进炎症性肠病中的炎症. 针对Tregs中的这种IL21诱导的代谢功能障碍,可以治疗慢性肠道炎症.

关键词:
炎症性肠道疾病是什么介质白血球蛋白 (Interleukins) 是一种细胞间的蛋白质.线粒体-ER对立的说法铁酸盐是什么 铁酸盐是什么监管T 细胞 监管T 细胞

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