由于传播的Candida krusei感染导致的严重高血症
Amenah Alghamdi1, Torrance Oravec2, Cesilia Nishi3
1Department of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada; Department of Medicine, Division of Infectious Diseases, King Abdulaziz University, Jeddah, Saudi Arabia.
概括
本案例研究详细介绍了一位患有复发性急性髓性白血病的患者的罕见传播的Candida krusei感染. 感染涉及多个器官并引起严重的高血症,成功地用抗真菌药物和ibrexafungerp治疗.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 散布的Candida krusei感染是一种罕见但严重的并发症,特别是在免疫功能低下的患者中.
- 长时间的中性质减退,通常在接受治疗的急性髓性白血病 (AML) 患者中看到,增加了对侵入性真菌感染的易感性.
- 由于其对可纳的内在耐药性,Candida krusei存在治疗挑战.
研究的目的:
- 报告在患有复发性急性髓性白血病的患者中传播的Candida krusei感染的罕见病例.
- 突出各种各样的器官参与和并发症,包括严重的高血症.
- 讨论治疗方法,包括亲肠道抗真菌药物和口服ibrexafungerp.
主要方法:
- 一个31岁的男性患有复发性AML的病例报告.
- 临床表现和诊断工作对扩散型 кандидоз.
- 治疗方案包括亲肠道抗真菌药物和随后的口服IBREXAFUNGERP治疗.
主要成果:
- 患者患有Candida krusei真菌病,广泛传播,影响皮肤,眼睛,脏,脏,骨髓和骨.
- 严重的高血症是一个显著的并发症.
- 该患者成功地接受了初始的肠道抗真菌药物治疗,随后接受了口服IBREXAFUNGERP治疗.
结论:
- 散布的Candida krusei感染可以发生在复发的AML和长期中性衰竭的患者中.
- 多系统性参与和高血是潜在的并发症,需要迅速识别和管理.
- Ibrexafungerp可能是这种具有挑战性的感染的可行的口服治疗选择.
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