与心脏起器相关的因素和Fontan患者的结果 - 节奏QRS持续时间对节奏QRS持续时间的影响
Hyewon Shin1, Jae Suk Baek1, Mi Jin Kim1
1Division of Pediatric Cardiology, Department of Pediatrics, Asan Medical Center Children's Hospital, Ulsan University College of Medicine.
概括
在Fontan患者中,永久心脏起器植入与糟糕的结果有关. 节奏较长的QRS持续时间超过153毫秒,预测这些个体的不良事件.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏病是一种先天性心脏病.
- 电子生理学 电子生理学
背景情况:
- 永久心脏起器 (PPM) 植入是Fontan手术后发病和死亡的已知风险因素.
- 了解影响Fontan患者PPM结果的因素对于改善患者护理至关重要.
研究的目的:
- 调查与接受PPM的Fontan生理学患者不良结果相关的临床,手术和设备相关因素.
- 在这个特定的患者群体中确定不良结果的预测因素.
主要方法:
- 分析了508名经过Fontan手术的患者的回顾性审查,其中32名接受PPM植入的患者.
- 临床因素,与Fontan程序相关的因素和与PPM相关的因素在表现不佳和表现良好的组之间进行比较.
- 接收器运行特征 (ROC) 曲线分析以确定节奏QRS持续时间的预测值.
主要成果:
- 结果较差的组 (死亡,心脏移植或Fontan失败) 显示了显著更长的平均节奏QRS持续时间 (P=0.044).
- 诸如心室形态,节奏模式和节奏率等因素在结果组之间没有显著差异.
- ROC分析发现153毫秒的节奏QRS持续时间截止值是不良结果的预测指标 (AUC=0.73,P=0.035).
结论:
- 延长节奏QRS持续时间与需要永久心脏起器植入的Fontan患者的不良结果有关.
- 节奏QRS持续时间可以作为一种有价值的预测标志物,用于识别风险更高的Fontan患者的不良结果.
相关概念视频
Decreased pulse rate
544
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
544
Pathophysiology of Cardiac Performance
663
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
663


