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子宫癌:美国印第安人/阿拉斯加原住民社区中可预防的死亡
Jessica Buck DiSilvestro1, Keely K Ulmer2, Madeline Hedges3
1Brown University, Providence, RI, USA; Women & Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA.
美国印第安人/阿拉斯加土著 (AI/AN) 个人面临两倍的宫癌死亡率. 查和HPV疫苗的不足利用,以及较高的感染率,需要为这个社区采取紧急的公共卫生干预措施.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防癌症 预防癌症
背景情况:
- 美国印第安人/阿拉斯加原住民 (AI/AN) 人口的宫癌死亡率是美国普通人口的两倍.
- 关键的预防策略,包括宫癌查和人类乳头瘤病毒 (HPV) 疫苗接种,在AI/AN社区普遍使用不足.
- AI/AN个体表现出较高的已确定的宫癌风险因素率,以及高风险HPV菌株感染的可能性增加,超出9价值疫苗所覆盖的高风险HPV菌株.
研究的目的:
- 突出美国印第安人/阿拉斯加本土人 (AI/AN) 之间宫癌结局和预防吸收的差异.
- 强调迫切需要加强针对AI/AN社区的宫癌预防和治疗策略.
主要方法:
- 这项研究是对有关AI/AN人群宫癌发病率,死亡率,风险因素和预防计划参与的现有数据和文献的综述.
- 对流行病学数据的分析,以确定宫癌负担和HPV感染率的差异.
主要成果:
- 与美国一般人口相比,AI/AN个体的宫癌死亡率是AI/AN个体的两倍.
- 在AI/AN社区中观察到,宫癌查和HPV疫苗接种服务的大量使用不足.
- 在AI/AN个体中,高风险HPV感染的发病率更高,包括目前疫苗未涵盖的菌株.
结论:
- 对于美国印第安人/阿拉斯加原住民 (AI/AN) 群体来说,有必要改善和准宫癌预防和治疗计划.
- 解决差异需要文化上适当的干预措施,以增加查和接种疫苗,并有效管理HPV感染.
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