相关实验视频

Updated: Jul 5, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

术内德克萨米他和慢性术后疼痛:对大型试验的倾向性得分匹配分析

Paul S Myles¹, Tomas B Corcoran², Matthew T Chan³

¹Department of Anaesthesiology and Perioperative Medicine, Alfred Hospital, Melbourne, VIC, Australia; Department of Anaesthesiology and Perioperative Medicine and Biostatistics Unit, School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia.

British journal of anaesthesia

|January 24, 2024

概括

在重大非心脏手术期间使用德克萨米他并不会增加患慢性术后疼痛 (CPSP) 的风险. 这项研究发现,接受德甲和不接受德甲的患者之间CPSP发病率没有显著差异.

科学领域:

麻醉学和疼痛管理
手术结果研究研究.

背景情况:

已知甲可以减少急性术后疼痛.
它对慢性术后疼痛 (CPSP) 的发展的影响仍然不确定.
这项研究调查了在进行重大非心脏手术后,手术内使用德克萨米他和CPSP之间的关联.

研究的目的:

为了确定单次手术内剂量德克萨米他是否会增加慢性术后疼痛 (CPSP) 发生率在12个月后,主要的非心脏手术.
分析德克萨米他对患者报告结果的影响,包括生活质量和疼痛干扰.

主要方法:

使用ENIGMA-II试验CPSP数据集进行了倾向性得分匹配分析.
基线变量使用倾向得分匹配和反向概率加权来平衡.
主要结局是手术后12个月CPSP的发生率.

主要成果:

分析包括2999名患者;11.9%的接受德甲和18.8%的不接受它报告CPSP (未经调整).
在倾向性得分匹配后,甲松组中CPSP的发病率为12.2%,对照组为13.8% (调整后风险比为0.88;P=0.493).
没有观察到生活质量或疼痛干扰的显著差异,尽管"最小疼痛"和"现在疼痛"得分在甲组中更高.

结论:

在手术期间使用德克萨米他似乎不会增加经过重大非心脏手术后慢性术后疼痛的风险.
研究结果表明,德克萨米他对于长期疼痛的发展是安全的.
进一步的研究可能会探索对特定疼痛特征的细微影响.

关键词:

麻醉学麻醉学麻醉学皮质类固醇是什么德克萨米他是一种疼痛疼痛疼痛疼痛人们的生活质量.手术手术手术手术手术手术手术

更多相关视频

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery

Published on: June 23, 2023

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

相关概念视频

Local Anesthetics: Clinical Application as Epidural Anesthesia

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...