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Updated: Jul 5, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Published on: May 22, 2014

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HECTD3通过阻断NLRP3-NEK7相互作用来抑制NLRP3炎症酶组合和激活

Zhuo Cheng1,2, Maobo Huang3, Wei Li1,2

  • 1Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650201, China.

Cell death & disease
|January 24, 2024
PubMed
概括

HECTD3通过阻断NEK7相互作用来抑制NLRP3炎症酶,减少诸如痛风性关节炎等炎症性疾病. 这一发现表明HECTD3是NLRP3相关疾病的潜在治疗点.

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