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合理的菌株设计,具有最小的表型干扰

Bharath Narayanan1,2, Daniel Weilandt1,3, Maria Masid4

  • 1Laboratory of Computational Systems Biology (LCSB), Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland.

Nature communications
|January 24, 2024
PubMed
概括

这项研究引入了一个计算框架,以加速为细胞工程设计基因干预的设计. 该方法有效地探索设计可能性,确保强大的微生物菌株以改善生物生产.

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Chi-square Analysis02:46

Chi-square Analysis

The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
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