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Updated: Jul 5, 2025

Measuring Single-Cell Mitochondrial DNA Copy Number and Heteroplasmy Using Digital Droplet Polymerase Chain Reaction
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与线粒体DNA复制号相关的核和线粒体遗传变异

Adriana Koller1, Michele Filosi2, Hansi Weissensteiner1

  • 1Institute of Genetic Epidemiology, Medical University of Innsbruck, Schöpfstrasse 41, 6020, Innsbruck, Austria.

Scientific reports
|January 24, 2024
PubMed
概括

新的研究发现了两个关键的基因位置,HBS1L和GSDMA,影响线粒体DNA复制数 (mtDNA-CN). 这项研究阐明了核和线粒体对mtDNA-CN调节的贡献,进步了对线粒体功能障碍生物标志物的理解.

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