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对抗微生物药物的激活机制的结构洞察 GBP1

Marius Weismehl1,2, Xiaofeng Chu3, Miriam Kutsch4,5,6,7

  • 1Structural Biology, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), 13125, Berlin, Germany.

The EMBO journal
|January 24, 2024
PubMed
概括

人体酸结合蛋白1 (GBP1) 形成抗微生物蛋白外套来对抗病原体. 结构数据揭示了GBP1双元如何组装成更高阶结构,协调先天免疫反应.

关键词:
迪纳明超级家族的超级家族电子显微镜电子显微镜这是一个GTPase.关酸盐结合蛋白质 关酸盐结合蛋白质寡合化是指一种氧化物.

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