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系统性免疫炎症指数与ST升高心肌梗塞患者中完全心房阻塞的发展之间的关系,这些患者接受了初级皮肤穿冠状动脉干预

Fatma Esin¹, Saban Esen², Semih Aktürk¹

¹Atatürk Training and Research Hospital, Department of Cardiology, Izmir Katip Çelebi University, Izmir, Turkey.

BMC cardiovascular disorders

|January 24, 2024

概括

系统性免疫炎症指数 (SII) 与接受PCI的STEMI患者中完全心房阻塞 (CAVB) 的风险更高有关. 这种随时可用的血液标志物可以帮助识别有风险的人.

科学领域:

心脏病学心脏病学
血液学血液学血液学
炎症研究炎症研究

背景情况:

系统性免疫炎症指数 (SII) 是一种反映系统性炎症和免疫状态的新标志物.
完全心房阻塞 (CAVB) 是ST升高心肌梗塞 (STEMI) 患者的一种严重并发症.
确定CAVB的预测标记对于风险分层和管理至关重要.

研究的目的:

调查SII和CAVB发生率在接受初级皮肤冠状动脉干预 (PCI) 的STEMI患者中之间的关联.

主要方法:

追溯分析883名接受初级PCI的STEMI患者.
从入院血液样本 (白细胞,中性粒细胞,血小板计数) 计算SII.
在患有CAVB和未患有CAVB的患者之间比较SII水平.

主要成果:

48名 (5.03%) 患者发生了CAVB.
在CAVB患者中观察到较高的SII水平 (1370比771,p<0.001).
多变量分析显示,SII和CAVB风险之间存在显著的正相关性 (OR:1.0003,P=0.044).
一个SII切线1117.7×109/L预测了CAVB,具有70.8%的灵敏度和65.6%的特异性 (AUC:0.714).

结论:

升高的SII水平与PCI后的STEMI患者中CAVB风险增加显著相关.
SII代表了一个潜在的有价值,廉价和可访问的生物标志物,用于早期识别高风险的CAVB患者.

关键词:

完整的心房静脉阻塞.主要的穿皮冠状动脉干预.ST升高心肌梗塞的心脏病发作系统性免疫炎症指数

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