如何在营养干预研究中测量生活质量:系统性审查
Raquel Clapés Pemau1, Patricia González-Palacios2,3, Kirk W Kerr4
1Abbott Nutrition, Granada, Spain.
Health and quality of life outcomes
|January 24, 2024
概括
这次系统性审查分析了营养干预研究中如何测量与健康相关的生活质量 (HRQoL). 它确定了常用的生活质量问卷 (QoLQ),以指导未来的营养研究.
科学领域:
- 营养科学 营养科学
- 医疗保健服务研究 医疗服务研究
- 患者报告的结果
背景情况:
- 营养干预措施显著影响患者的健康,影响疾病特异性疾病和与健康相关的生活质量 (HRQoL).
- 评估营养护理对HRQoL的影响对于全面的患者评估至关重要.
- 本综述系统地检查了以营养干预为重点的研究中HRQoL的测量.
研究的目的:
- 系统地审查和识别用于评估营养干预措施的研究中的生活质量问卷 (QoLQ).
- 分析这些QoLQ在不同患者群体,年龄组和疾病类别中的应用.
- 为研究人员在未来营养干预研究中选择适当的QoLQ提供指导.
主要方法:
- 在EMCare,EMBASE和Medline数据库中进行了系统的文献搜索.
- 通过使用与HRQoL和营养疗法,饮食疗法或食补充剂相关的关键词来确定研究.
- 包括标准包括HRQoL和营养干预术语在标题,摘要或MeSH分类中,其次是标题,摘要和全文评论.
主要成果:
- 包括116项研究,确定了14项一般性和25项疾病特异性 QoLQ.
- 最常用的一般QOLQ是简短形式的36项健康调查 (SF-36) 和EuroQol5维 (EQ-5D).
- 欧洲癌症研究和治疗组织 (EORTC-QLQ) 的生活质量问卷是最常见的疾病特定工具,特别是在与癌症相关的研究中. 在QoLQ使用方面注意到了区域差异 (例如,欧洲的EQ-5D,北美的SF-36).
结论:
- 在营养干预研究中,QoLQ用于测量HRQoL的使用已经得到了很好的确立.
- 一般和特定疾病的QoLQ都可用,并在科学文献中得到了利用.
- 进一步的研究应该探索综合使用一般和特定疾病的QoLQ,以全面评估营养干预对HRQoL的影响.
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