来自中国南京的绝经后妇女的HPV流行和分布特征
Xiaorui Yin1, Chunxue Zhang1, Xiaoqing Wu1
1Department of Gynecology, Nanjing First Hospital, Nanjing Medical University, No.68, ChangLe Road, Nanjing, 210006, China.
BMC women's health
|January 24, 2024
概括
人类乳头瘤病毒 (HPV) 感染了中国南京22.36%的绝经后妇女. HPV52,HPV58和HPV53是最常见的类型,强调了针对性预防策略的必要性.
科学领域:
- 妇科 妇科医生 妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 子宫癌与人类乳头瘤病毒 (HPV) 感染密切相关.
- 了解特定的人口结构中的HPV患病率对于公共卫生倡议至关重要.
研究的目的:
- 确定HPV基因型在中国南京的绝经后妇女中的流行率和分布.
- 为了确定常见的HPV类型,并评估这个人口中不同年龄组的感染率.
主要方法:
- 在南京第一医院 (2019-2021) 对14608名绝经后妇女 (45-90岁) 的HPV检测数据进行了回顾性分析.
- 对23种HPV基因型进行检测.
- 使用奇平方测试来评估感染率和基因型分布的统计分析.
主要成果:
- 在绝经后的女性中,HPV感染率为22.36%.
- 患病率因年龄而异:19.54% (≤50),24.30% (51-60),26.58% (61-70),和14.99% (≥71) 的情况.
- 最常见的基因型是HPV52 (22.13%),HPV58 (15.86%),HPV53 (14.17%),HPV16 (12.61%) 和HPV81 (11.66%).这些都是最常见的基因型. 单个感染率为14.23%,多个基因型感染率为8.14%.
结论:
- 在南京的绝经后妇女的年龄组中,HPV感染率和常见的基因型不同.
- 这些发现强调了HPV特定人群流行病学数据的重要性.
- 结果可以为有针对性的预防和查策略提供信息,以减少与HPV相关的疾病负担.
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