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Updated: Jul 5, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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通过METTL1介导的tRNA m7G修饰,通过tRNA调节的翻译控制促进AML的白血病发生

Pan Zhao1,2, Lin Xia1, Dan Chen1

  • 1Medical Center of Hematology, Xinqiao Hospital of Army Medical University, Chongqing, 400037, China.

Experimental hematology & oncology
|January 24, 2024
PubMed
概括

升高的METTL1/WDR4通过破坏tRNA的稳定性和增加tsRNA生物发生,促进急性髓性白血病 (AML). 针对METTL1/WDR4可能为AML患者提供新的治疗策略.

关键词:
在AML,AML就是AML.在METTL1/WDR4中使用METTL1/WDR4.翻译控制 翻译控制m7GG 在线观看在tRNA修改过程中.

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