COVID-19 Omicron 变种感染对孕产妇和新生儿的结果影响最小:一个横截面队列研究
Liu Ying1, Liang Mengmeng1, Zhang Lan1
1Delivery Room, Shanghai First Maternity and Infant Hospital, Tongji University, Shanghai, China.
Nursing open
|January 25, 2024
概括
欧米克朗变种与增加孕产妇发烧和更高的阴道分娩早产率有关. 然而,大多数孕产妇和新生儿结局仍然不受COVID-19感染的影响.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 新生儿医学 新生儿医学
背景情况:
- SARS-CoV-2 的 Omicron 变种已经成为一个重大的全球健康问题.
- 了解它对怀孕和新生儿的影响对于临床管理至关重要.
- 以前的研究表明,COVID-19变种对孕产妇和新生儿健康有不同的影响.
研究的目的:
- 调查Omicron变异对母亲和新生儿结局的特定影响.
- 为了比较COVID-19阳性和阴性妇女在分娩期间的结果.
- 为了识别Omicron感染的任何传递方式特定影响.
主要方法:
- 进行了一项横截面队列研究,涉及2022年12月在上海活产的妇女.
- 对人口统计数据,母亲/新生儿结局和实验室结果进行了医疗记录审查.
- 倾向性得分匹配用于创建可比的COVID-19阳性和阴性组进行分析.
主要成果:
- 这项研究包括1508名女性,310个匹配对 (COVID-19阳性与阴性) 用于分析.
- 在所有分娩方式中,COVID-19阳性女性经历了更高的孕产妇发烧率.
- 在COVID-19阳性母亲的阴道分娩与更高的早产率和较低的动脉血气pH相关.
结论:
- 怀孕期间的Omicron感染可能导致孕妇发烧增加和新生儿不良后果,特别是早产,在阴道分娩.
- 大多数其他孕产妇和新生儿结局在受感染和未受感染的母亲之间没有显著差异.
- 需要进一步的研究,以充分阐明Omicron感染怀孕的长期影响和管理策略.
更多相关视频
14:43A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
11.8K
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.1K
相关概念视频
Factors Affecting the Risk of Infection
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Bias in Epidemiological Studies
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
