相关实验视频

Updated: Jul 5, 2025

Author Spotlight: Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration

Author Spotlight: Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration

Published on: June 9, 2023

不孕女性脂肪分布差异与辅助生殖结果的关联:一项前性队列研究

Xiao-Huan Song^1,2, Meng-Li Zhu³, Chao Zhang^1,2,4

¹Department of Health Promotion and Behavioral Sciences, School of Public Health, Anhui Medical University, Hefei, Anhui, China.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

|January 25, 2024

概括

较高的体脂会对生育治疗产生负面影响. 腿部脂肪量增加与较少的卵细胞,胚胎和胚胎相关,这表明脂肪分布是辅助生殖成功的关键.

科学领域:

生殖医学生殖医学
内分泌学在内分泌学.
身体组成分析身体成分分析

背景情况:

辅助生殖技术 (ART) 对于不孕症治疗至关重要.
了解影响ART成功的因素对于优化患者治疗结果至关重要.
除了整体肥胖之外,脂肪分布可能会显著影响生殖健康.

研究的目的:

研究身体脂肪分布对不孕妇女辅助生殖技术 (ART) 结果的影响.
确定与ART成功率相关的特定脂肪储存,如内脏和腿部脂肪.

主要方法:

招募了接受ART的576名不育妇女的队列.
评估了身体组成和脂肪分布,包括腿部脂肪质量 (LBFM) 和内脏脂肪.
多因素后勤回归和受限立方线 (RCS) 模型分析了脂肪分布和ART结果 (卵细胞,胚胎,胚胎) 之间的关系.

主要成果:

较高的总体脂肪质量与卵细胞,卵胞 (2PN) 和可用的胚胎数量有负相关.
腿部体脂质量 (LBFM) 与生殖结果有显著的关联.
内脏脂肪水平与ART结果没有显著的相关性.
RCS建模证实了LBFM和ART成功之间的线性剂量反应关系.

结论:

不孕妇女的脂肪分布模式与ART结果有关.
增加的总体脂肪和特别是腿部脂肪质量与辅助生殖的成功率降低有关.
这些发现强调了在不孕症管理中考虑身体组成的重要性,而不仅仅是BMI.

关键词:

美国国务院调查局 (ICSI)辅助生殖技术是一种辅助生殖技术.身体质量指数 (BMI) 是什么?脂肪的分布脂肪的分布在体外受精体外受精.不孕症不孕不育不孕不育不孕不育

更多相关视频

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

相关概念视频

Infertility in Females

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...

Infertility in Males

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...