轻度创伤性脑损伤和情绪和行为障碍的风险
Richard L Delmonico1,2, Lue-Yen Tucker3, Brian R Theodore1,2
1Kaiser Foundation Rehabilitation Center, Kaiser Permanente Vallejo Medical Center, Vallejo, California.
Pediatrics
|January 25, 2024
概括
儿童轻度创伤性脑损伤 (mTBIs) 在受伤后的四年内显著增加了新的情感和行为障碍的风险. 早期查对于识别和管理这些条件至关重要,以帮助恢复.
科学领域:
- 儿科神经学 儿科神经学
- 儿童精神病学 儿童精神病学
- 神经科学是一个神经科学.
背景情况:
- 儿童轻度创伤性脑损伤 (mTBIs) 与精神问题有关.
- 之前的研究存在设计局限性,后续时间短,结果定义不清楚.
- 需要对儿科mTBI精神病学后果的强大,长期数据.
研究的目的:
- 确定轻度创伤性脑损伤 (mTBI) 后4年内儿童出现新的情感和行为障碍的发生率和相对风险.
- 通过使用大量的队列和长期跟踪来解决先前研究的局限性.
- 为儿童群体提供基于证据的推,用于mTBI后的精神病治疗.
主要方法:
- 一项队列研究设计,将儿科mTBI病例 (N=18,917) 与综合医疗保健系统内的匹配对照 (N=37,834) 进行比较.
- 参与者是2000年至2014年间被诊断患有mTBI的年龄≤17岁的儿童.
- 评估结果包括伤害或参考日期后4年内对情感或行为障碍的新诊断,年龄,性别,种族/种族和访问日期的匹配.
主要成果:
- 在受伤后的前三年里,mTBI组对情感障碍的调整风险显著更高 (在第二年增加了34%).
- 在受伤后的2年和4年观察到对行为障碍的显著调整风险 (高达37%的增加).
- 10~13岁的儿童患受伤后情绪和行为障碍的风险最高.
结论:
- 经历轻度创伤性脑损伤 (mTBI) 显著提高了儿童新发情感或行为障碍的风险,长达4年.
- 建议在儿科mTBI后进行常规和持续的精神疾病查.
- 早期识别持久的情感和行为障碍可以减轻恢复障碍.
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