相关实验视频
Updated: Jul 5, 2025

07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
23.6K
在整形手术中注射减肥药物:我们所知道的,外科手术期间的考虑,以及未来的建议
Elizabeth S O'Neill1, Aaron L Wiegmann1, Naomi Parrella2
1From the Division of Plastic and Reconstructive Surgery, Department of Surgery, Rush University Medical Center, Chicago, Ill.
Plastic and reconstructive surgery. Global open
|January 25, 2024
概括
注射式减肥药物如西马格卢提德是很受欢迎的,但影响了整形手术. 外科医生需要了解这些GLP-1激动剂,以确保患者的安全性和程序的结果.
科学领域:
- 内分泌学和新陈代谢学
- 整形外科 整形外科 整形外科
背景情况:
- 肥胖在美国是一个重要的公共卫生问题.
- 可注射药物,主要是类似葡萄糖的-1受体激动剂 (GLP-1RA),如黄,越来越多地用于体重控制.
- 这些药物,包括Ozempic,Wegovy,Saxenda和Mounjaro,在社交媒体上被广泛讨论,导致明显的身体变化.
研究的目的:
- 通知整形外科医生关于GLP-1RA用于减肥的日益增长的使用.
- 突出了解这些药物的适用性,适用性和术后管理的重要性.
- 讨论GLP-1RA对整形外科手术程序和患者结果的影响.
主要方法:
- 关于GLP-1RA在体重管理中的使用的文献综述.
- 分析GLP-1RA对身体组成和美学结果的影响.
- 讨论对整形手术实践的临床影响.
主要成果:
- GLP-1 RAs有效地促进体重减轻,导致显著的形态变化.
- 有有限的现有文献专门解决了对整形外科手术的影响.
- 广泛使用需要外科医生对患者选择和手术规划的认识.
结论:
- 整形外科医生必须了解GLP-1RA,以便有效管理正在接受或考虑进行美容手术的患者.
- 了解外科手术期间的考虑对于优化手术结果和患者安全至关重要.
- 需要进一步的研究,以充分阐明整形外科的长期影响和最佳管理策略.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
88
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
88
Parenteral Anesthetics: Overview
127
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
127
Insulin: Dosing Regimen and Adverse Effects
174
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
174
Drug Delivery: Parenteral Route
532
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
532
Glucagon-like Receptor Agonists
323
Incretins include glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which stimulate insulin secretion post-meals. In type 2 diabetes, GIP's efficacy is reduced, making GLP-1 a viable drug target. GIP originates from preproGIP.
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...
323
Insulin Formulations: Types and Delivery
197
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
Short-acting insulins are divided into...
197

