儿童的性食道炎:来自第三级护理中心的横截面研究
Arghya Samanta1, Ujjal Poddar1, Niraj Kumari2
1Department of Pediatric Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow India.
JGH open : an open access journal of gastroenterology and hepatology
|January 25, 2024
概括
在印度,性食道炎 (EOE) 影响3.5%的儿童接受上部胃肠内镜检查. 用质子抑制剂 (PPI) 及时治疗导致所有诊断病例的缓解.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 胃肠内镜检查 胃肠内镜检查
背景情况:
- 埃索诺菲尔性食道炎 (EoE) 的患病率在全球范围内不断增加,但印度次大陆的数据很少.
- 了解印度儿童的EoE患病率对于诊断和管理至关重要.
研究的目的:
- 确定在接受选择性上部胃肠内镜检查 (UGIE) 的儿童中EoE的患病率.
- 评估这一儿科群体中EoE的临床特征和治疗结果.
主要方法:
- 一项前性横截面研究招募了200名接受UGIE的儿童.
- 分析了食道,胃和十二指肠活检以检测埃索诺菲尔细胞数量 (≥15/HPF用于EoE诊断).
- 记录了临床数据,内镜检测结果和治疗反应.
主要成果:
- 基于医院的EoE患病率为3.5% (200名儿童中7名).
- 缺食症和食物玻尿酸影响是关键指标,分别在20%和67%的病例中发现了EdE.
- 伴随性疾病包括喘 (43%) 和外围好色素 (28.5%).
结论:
- 在接受UGIE的印度儿童中存在EoE,患病率为3.5%.
- 质子抑制剂 (PPI) 疗法,单独或与狭窄扩张,导致临床,内镜和组织病理学缓解.
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