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Updated: Jul 5, 2025

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
06:38

High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy

Published on: February 7, 2019

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转录因子结合位点的位置特定演变,以及F81模型的快速概率计算

Pavitra Selvakumar1,2, Rahul Siddharthan1,2

  • 1The Institute of Mathematical Sciences, Chennai, India.

Royal Society open science
|January 25, 2024
PubMed
概括

新的位置特定静止向量 (PSSV) 揭示了核酸适应性如何塑造转录因子结合位 (TFBS) 进化. 这种方法揭示了祖先核酸对DNA序列施加的进化压力.

关键词:
补偿性突变是一种补偿性突变.进化 演化 演化 演化 演化 演化 演化 演化转录因子的结合部位.

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