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患者状态指数,双光谱指数和在印度患者中诱导普罗波的临床参数之间的比较:一项前性研究

Mohammed Shafiq Shajahan¹, Sanjay Agrawal¹, Deepak Singla¹

¹Department of Anaesthesia, AIIMS, Rishikesh, Uttarakhand, India.

Journal of anaesthesiology, clinical pharmacology

|January 25, 2024

概括

与患者状态指数 (PSI) 监测器相比,双光谱指数 (BIS) 监测器在麻醉诱导过程中需要更少的propofol. 无论是BIS还是PSI监测都可与临床评估对普罗波剂量进行比较.

科学领域:

麻醉学麻醉学
药理学药理学是指药理学的学科.
医疗器械医疗器械

背景情况:

患者状态指数 (PSI) 和双谱指数 (BIS) 常用于监测麻醉深度.
这些指数指导了用于诱导的普罗波福尔剂量.
观察者评估警觉/镇静量表 (OAA/S) 是评估镇静的临床方法.

研究的目的:

为了比较PSI,BIS和OAA/S在引导propofol剂量的麻醉诱导中的有效性.
为了确定一个监测方法是否需要比其他方法少得多的propofol.

主要方法:

74名接受了腹腔镜胆囊切除术的患者被分为三组.
使用PSI监测A组,使用BIS监测B组,使用OAA/S监测C组.
诱导终点被定义为PSI 25±2,BIS 48±2或OAA/S ≤2.2.

主要成果:

诱导时的平均普罗波福尔剂量为2.23毫克/千克 (PSI),2.05毫克/千克 (BIS) 和2.11毫克/千克 (OAA/S).
B组 (BIS) 需要比A组 (PSI) (P=0.01) 低得多的 пропофол剂量.
血液动力学变量和并发症在所有组中都是可比的.

结论:

双光谱指数 (BIS) 监测结果显示,与患者状态指数 (PSI) 相比,在麻醉诱导过程中,对普罗波福尔的需求明显较低.
无论是BIS还是PSI监测都与临床OAA/S方法用于定位普罗波福尔剂量相匹配.
这些发现支持使用电生理学监测来优化麻醉药物管理.

关键词:

双光谱指数监测器监控观察者对警觉/镇静量级的评估患者状态指数患者状态指数意识监视器监视意识监视器.腹腔镜胆固醇切除术腹腔镜胆固醇切除术

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