基于标准体重的I-凝选择和基于小儿病人的面积的I-凝选择的比较 - 一项随机对照研究
Roopa Sachidananda1, Latha V Petkar1, Milon V Mitragotri1
1Department of Anaesthesiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Journal of anaesthesiology, clinical pharmacology
|January 25, 2024
概括
那纳尔突出维度为儿童患者选择正确尺寸的i-gel supraglottic气道装置提供了一个可行的体重替代方案,确保安全有效的气道管理.
科学领域:
- 麻醉学 麻醉学
- 儿科气道管理 儿童气道管理
- 医疗器械技术 医疗器械技术
背景情况:
- 包括i-gel在内的超节气道装置越来越多地用于儿科患者的气道管理.
- 标准i-gel尺寸的选择取决于患者的体重,这可能并不总是可行的.
- 需要使用替代方法来选择i-gel尺寸,以确保设备的最佳适应性和功能.
研究的目的:
- 为了比较基于体重的疗效与基于尺寸的方法来选择儿科患者的I-gel大小.
- 为了评估第一次尝试的成功率,插入的方便性,以及与每个尺寸方法相关的并发症.
主要方法:
- 一项前性随机研究涉及74名接受全身麻醉的儿科患者 (6个月至15岁).
- 患者被分为两组:基于体重的i-gel选择 (A组) 和基于尺寸的名选择 (B组).
- 使用统计测试 (学生的t测试,奇方测试) 分析了成功率,插入容易度和并发症.
主要成果:
- 群体之间的人口统计数据是可比的.
- 第一次尝试的成功率为97.4% (基于重量) 和91.7% (基于卓越),没有统计学上显著的差异 (P = 0.358).
- 两例在thenar杰出组的插入失败,和两个经历了轻微的血染;没有报告的重大并发症.
结论:
- 托纳尔卓越度维度作为一个实用的替代权重为儿科i-gel尺寸选择.
- 这种方法的成功率与基于体重的选择相似,轻微并发症的发生率很低.
- 这些发现支持在重量无法或不切实际的情况下使用thenar卓越方法来测量i-gel尺寸.
相关概念视频
01:52Regression Toward the Mean
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
01:13Randomized Experiments
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:28Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
01:12Hazard Ratio
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial evaluating a...
For example, in a clinical trial evaluating a...