患有COVID-19后疾病的个体的睡眠质量:与情绪,认知和功能变量之间的关系
A Carnes-Vendrell1, G Piñol-Ripoll1, M Ariza2
1Cognitive Disorders Unit, Cognition and Behavior Study Group, Hospital Universitari Santa Maria, Lleida, Spain.
在COVID-19后病情 (PCC) 患者中,睡眠质量差与抑郁症,焦虑和身体活动减少有关. 解决这些因素可能会改善PCC幸存者的睡眠.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 后COVID-19状态 (PCC) 影响了大量的个人,通常伴随着影响日常生活的持续症状.
- 在PCC患者中经常报告睡眠障碍,但其预测因素和与其他健康变量之间的关系需要进一步调查.
研究的目的:
- 评估PCC患者的睡眠质量.
- 确定睡眠质量差的预测因素,包括情绪,认知和功能变量.
- 根据COVID-19的严重程度来探索睡眠质量的差异.
主要方法:
- 该研究包括368名PCC患者和123名来自NAUTILUS项目的健康对照 (HC).
- 参与者填写了评估睡眠质量 (PSQI),焦虑 (GAD-7),抑郁 (PHQ-9),认知 (MoCA),记忆 (MFE-30),疲劳 (CFQ),生活质量 (EQ-5D) 和身体活动 (IPAQ) 的验证问卷.
- 进行了多次线性回归分析,以确定不同PCC严重程度组 (非住院,住院,ICU) 睡眠质量差的预测因素.
主要成果:
- 与HC相比,PCC患者的睡眠质量明显较差 (p < 0.0001).
- 抑郁症 (PHQ-9) 预测轻度PCC的睡眠不足;焦虑症 (GAD-7) 和生活质量 (EQ-5D) 预测住院PCC的睡眠不足.
- 焦虑 (GAD-7) 和体力活动 (IPAQ) 预测了ICU-PCC患者的睡眠不足.
结论:
- 在PCC中,睡眠质量较差与更高水平的抑郁和焦虑,生活质量下降和体力活动较低有关.
- 针对心理痛苦,生活质量和体力活动的治疗干预可以改善PCC患者的睡眠质量.
- 这些发现突显了PCC睡眠障碍的多因素性质,并为开发综合管理策略提供了信息.
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