重复雌激同步治疗对乳山羊激素分泌,生长和发育的影响
Shuang Sun1, Ming Lv2, Huimin Niu2
1College of Life Science and Agricultural Engineering, Nanyang Normal University, Nanyang, Henan, China.
Frontiers in veterinary science
|January 25, 2024
概括
在使用孕母马血清淋巴激素 (PMSG) 和孕激素 (P4) 的乳山羊中,重复的雌激素同步 (ES) 降低了生育能力. 这种下降与抗PMSG抗体的增加和荷尔蒙水平的改变有关,这影响了密集农业的生殖效率.
科学领域:
- 生殖内分泌学和动物科学
- 畜牧业管理和生育率优化
- 乳制品山羊的生产系统
背景情况:
- 密集的乳山羊养殖经常使用期同步 (ES) 进行繁殖管理.
- 羊的生殖性能可能会随着重复的ES治疗而下降,但潜在的机制尚未完全理解.
- 了解这些机制对于提高大规模运营中的育种效率至关重要.
研究的目的:
- 调查重复的孕母马血清性腺激素 (PMSG) 和孕激素 (P4) 介导的ES对乳山羊生育能力的影响.
- 为了确定重复ES治疗后影响生殖表现的关键代谢和内分泌因素.
- 阐明与频繁的ES协议相关的生育能力下降背后的机制.
主要方法:
- 四十八个Saanen做分为两个组:一个接收ES每两周三次 (3-PMSG) 和另一个一次 (1-PMSG).
- 雌激素同步涉及阴道内孕激素 (P4) 装置和PMSG注射.
- 测量了荷尔蒙水平 (FSH,LH,GnRH,黑色素,GH,PMSG,E2,P4),PMSG抗体水平,以及生殖参数 (雌激和生育率).
主要成果:
- 重复的ES治疗显著降低了乳山羊的和生育率.
- 在治疗后观察到在特定时间点上升的雌激素 (E2) 和孕 (P4) 水平.
- 在重复ES后检测到针对PMSG的抗体水平增加,与有效性降低相关.
结论:
- 抗PMSG抗体水平升高是山羊重复ES治疗效率降低的主要原因.
- 在某些阶段,高雌激素和孕水平可能会对生殖能力产生负面影响.
- 结果提供了反复PMSG刺激对代谢效应的见解,指导将来在山羊育种中使用激素.
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