预测对抗COVID-19的身体组成:一个潜在的数字健康战略
Seogsong Jeong1,2, Yo Hwan Lim1,2, Myeong Hoon Lee1,2
1Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, Republic of Korea.
Studies in health technology and informatics
|January 25, 2024
概括
更高的瘦身量和骨肌肉质量可能会降低肥胖男性的COVID-19风险. 然而,增加的身体成分指数与肥胖的COVID-19患者中更高的ECMO风险有关.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 身体组成分析 身体成分分析
背景情况:
- 2019年冠状病毒病 (COVID-19) 疫情凸显了了解影响疾病风险和严重性的宿主因素的重要性.
- 身体组成,包括瘦身量,骨肌量和身体脂肪,在代谢健康和免疫功能中起着至关重要的作用.
研究的目的:
- 调查预测的瘦身量指数 (LBMI),尾骨肌量指数 (ASMI) 和身体脂肪量指数 (BFMI) 与COVID-19风险和结果之间的关联.
- 为了检查体质成分指数的变化如何与COVID-19的发病率和需要体外膜氧化 (ECMO) 在一个大群体队列.
主要方法:
- 利用了全国范围的,基于人口的超过200万名非体重不足的参与者的队列.
- 连续两年进行两次健康查检查,以估计预测的身体成分指数的变化.
- 应用多变量调整后勤回归模型来分析身体组成和COVID-19结果之间的关联.
主要成果:
- 增加的LBMI和ASMI与患有肥胖症的男性中COVID-19风险降低有关.
- 在COVID-19患者中,高LBMI,ASMI和BFMI与需要体外膜氧化的风险增加有关,特别是在肥胖男性中.
结论:
- 身体成分指标,特别是瘦身和骨肌肉质量,表明与男性的COVID-19风险和严重程度存在复杂的关系.
- 研究结果表明,虽然较高的肌肉质量可能会保护肥胖男性免受初始感染,但在严重的COVID-19病例中,需要先进的呼吸系统支持,这可能与更糟糕的结果有关.
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