心血管疾病中的访问到访问的血压变化
Mifetika Lukitasari1, Siaw-Teng Liaw1, Bin Jalaludin1
1School of Population Health, UNSW Sydney, NSW 2052 Australia.
Studies in health technology and informatics
|January 25, 2024
概括
访问到访问的血压变化 (BPV) 影响心血管疾病 (CVD) 风险. 使用电子健康记录 (EHR) 和临床试验的研究表明数据收集和BPV测量指标存在差异.
科学领域:
- 心血管医学 心血管医学
- 医疗信息学 医疗信息学
- 临床研究方法论 临床研究方法论
背景情况:
- 访问到访问的血压变化 (BPV) 是心血管疾病 (CVD) 的公认危险因素,独立于平均血压 (BP).
- 在常规的临床实践中,BPV经常被忽视,并被视为随机波动而不是显著的临床指标.
- 在不同的数据源中,BPV如何评估和解释存在差异.
研究的目的:
- 为了比较研究的方法和研究结果,检查访问到访问BPV和CVD之间的关联.
- 调查电子健康记录 (EHR) 数据和临床试验数据之间的数据采集和BPV估计差异.
- 确定缺乏对BPV评估标准化指标的共识.
主要方法:
- 对现有文献和研究进行比较审查.
- 对临床试验中的数据收集协议与EHR数据的分析.
- 检查用于量化BPV的各种指标.
主要成果:
- 临床试验数据中的血压 (BP) 值遵循比EHR数据更严格的协议.
- 在用于估计跨研究BPV的指标中观察到显著的异质性.
- 没有确定BPV测量的标准化方法.
结论:
- 数据收集和BPV指标的变化在研究中比较研究结果时带来了挑战.
- 标准化BP测量协议和BPV估计指标对于准确的CVD风险评估至关重要.
- 需要进行进一步的研究,以建立在现实临床环境中评估BPV的一致方法.
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