与胡须龙相关的沙门氏菌维特金疫情,加拿大和美国,2020-2022年
Emerging infectious diseases
|January 25, 2024
概括
加拿大的两个婴儿沙门氏菌维特金感染与物胡须龙有关. 这种罕见的沙门氏菌血清病毒爆发也影响了美国的婴儿,突显了为早期检测提供跨境数据共享的必要性.
科学领域:
- 动物传播疾病 动物传播疾病
- 传染病流行病学 传染病流行病学
- 微生物基因组学 微生物基因组学
背景情况:
- 沙门氏菌 (Salmonella enterica serovar Vitkin) 是一种罕见的病原体.
- 爬行动物,特别是胡须龙,是已知的沙门氏菌的储库.
- 跨境合作对于追踪传染病爆发至关重要.
研究的目的:
- 报告和描述与加拿大和美国的胡须龙有关的沙门氏菌维特金疫情.
- 使用全基因组测序研究疫情菌株的遗传相关性.
- 强调共享基因组数据对于公共卫生监测的重要性.
主要方法:
- 病例鉴定和流行病学调查.
- 全基因组测序 (WGS) 用于分子亚型化.
- 核心基因组多部位序列类型化 (cgMLST) 用于等位基因差异计算.
- 环境采样和病原体隔离.
主要成果:
- 2022年在加拿大安大略省发现了两个婴儿沙门氏菌维特金病例,与物胡须龙有关.
- 这种疫情菌株是从胡须龙中分离出来的.
- 在2021年3月至2022年9月期间,在美国发生了12起相关病例,其中大多数是1岁以下的婴儿,报告有胡子龙接触.
- 追踪发现了东南亚胡子龙的潜在常见供应商.
结论:
- 胡子龙是沙门氏菌向人类传播的可能来源.
- 卫生标志系统和国家间数据共享对于检测和应对罕见的沙门氏菌血清病毒爆发至关重要.
- 加拿大和美国之间的加强监测和沟通可以改善早期发现疫情.
相关概念视频
01:51Vaccinations
44.5K
Overview
44.5K
00:57Viral Recombination
23.4K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.4K
01:50Threats to Biodiversity
22.3K
There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
22.3K