低和边缘脚-手臂指数与内动脉瘤有关:一项回顾性队列研究
Dan Laukka1,2, Essi Kangas3,4, Aino Kuusela3
1Department of Neurosurgery, Neurocenter, Turku University Hospital, Turku, Finland.
Neurosurgery
|January 25, 2024
概括
低的脚-手臂指数 (ABI) 与未破裂的内动脉瘤 (IAs) 的明显更高的患病率有关. 这一发现表明,ABI可能有助于识别IA风险增加的个体.
科学领域:
- 血管医学 血管医学
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 较低的脚-手臂指数 (ABI) 与全身炎症和心血管事件风险增加有关.
- 内动脉瘤 (IAs) 与其他心血管疾病具有共同的风险因素.
- ABI和IA患病率之间的关联仍未得到充分研究.
研究的目的:
- 调查脚-手臂指数 (ABI) 值与未破裂的内动脉瘤 (IAs) 的患病率之间的关系.
主要方法:
- 对776名脑血管成像或IA诊断的患者进行了回顾性队列研究.
- 根据ABI,患者被分为四组:低ABI (≤0.9),边界ABI (0.91-0.99),高ABI (>1.4) 和正常ABI (1.00-1.40).
主要成果:
- 与正常ABI (2.4%) 相比,低ABI (20.3%) 和边缘ABI (14.9%) 组中IA的患病率显著更高.
- 低ABI (OR,13.02) 和边界ABI (OR,8.68) 经调整后与未破裂的IA有很强的关联.
- 在ABI组之间没有观察到破裂IA患病率的显著差异.
结论:
- 没有破裂的IA的患病率在患有低或边缘ABI的个体中显著更高.
- ABI测量可以作为一种有价值的临床工具,用于识别患有内动脉瘤风险较高的个体.
- 调查结果表明,ABI可以为IA的查和预防策略提供信息.
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