一种科学开发和标准化的草药酒精消毒剂的抗微生物疗效
Rajkumar Tulsawani1, Kalyani Verma2, Ekta Kohli2
1Defence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India. rktulsawani@yahoo.com.
Archives of microbiology
|January 25, 2024
概括
在30秒内,两种新的草药酒精洗手剂有效地将微生物负载降低了99.99%. 与世卫组织推的消毒剂相比,这些天然手部卫生产品的疗效和安全性更高.
科学领域:
- 微生物学 微生物学
- 药理学 药理学 是一个学科.
- 公共卫生 公共卫生
背景情况:
- 手是传染感染的主要途径,包括SARS-CoV-2和其他疾病.
- 有效的手部卫生对于预防疾病传播至关重要,尤其是在流行病期间.
- 传统的基于酒精的洗手液是广泛推的,但可能有缺点.
研究的目的:
- 评估两种基于植物酒精的新型手部消毒剂的抗菌和抗病毒疗效.
- 为了比较这些草药消毒剂与标准的基于酒精的消毒剂的性能.
- 评估开发的草药手洗手剂的安全性和用户可接受性.
主要方法:
- 在MDCK细胞上对流感A病毒进行体外抗病毒活性测试.
- 抗微生物敏感性测试方法,以确定微生物负载的减少.
- 在体内对志愿者进行体内测试,以评估疗效,皮肤刺激和享乐性质.
主要成果:
- 两种草药消毒剂 (HS1和HS2) 在30秒内将微生物负载降低了99.99%.
- 在志愿者测试中,HS1和HS2与世卫组织推的基于酒精的消毒剂相比,显示出更高的疗效.
- HS2表现出增强的抗病毒有效性,更好的用户效率和快乐的品质,而不会引起皮肤刺激或干燥.
结论:
- 含有Azadirachta indica,Citrus limon,Zingiber officinale,Aloe vera和Ocimum sanctum的草本酒精基手消毒剂是有效的抗微生物和抗病毒剂.
- 这些新型消毒剂为手部卫生提供了有希望的替代品,提高了效率和用户体验.
- 开发的草药消毒剂对皮肤是安全的,具有更长的保质期,并有助于有效地减少微生物负载.
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