更有组织的白质与老年人的积极性偏见有关
Petra V Viher1, Johanna Seitz-Holland1,2, Marc S Schulz3
1Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Brain imaging and behavior
|January 25, 2024
概括
健康的老年人表现出记忆中的积极性偏见,他们更喜欢积极而不是中立的信息. 这种偏见与前脑连接中的更好的白质完整性有关,这表明与年龄相关的情绪处理的神经基础.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 老年学是指老年学的学科.
背景情况:
- 健康的老年人表现出一种积极性偏见,他们更喜欢积极的,而不是中性或负面的刺激.
- 这种偏见与记忆和注意力有关,涉及相互连接的大脑区域.
- 积极性偏差和白质完整性在衰老中的联系还不太清楚.
研究的目的:
- 研究白质组织与老年人积极性偏差之间的关系.
- 为了确定白质完整性是否与记忆对积极与中性或负面信息的记忆相关.
主要方法:
- 收集了25名健康老年人的行为和扩散权重磁共振成像 (dMRI) 数据.
- 从功能记忆任务中计算了Pos-Neg和Pos-Neu得分.
- 使用基于通路的空间统计 (TBSS) 和非参数变量测试来分析白质完整性.
主要成果:
- 在前脑连接中的Pos-Neu得分和白质完整性之间发现了显著的积极关联.
- 在对年龄,性别和教育进行控制后,这种关联仍然很重要.
- 当口头情节性记忆作为共变量被纳入时,它的意义就消失了.
结论:
- 老年人记忆中的积极性偏差与前额连接中的较大白质组织有关.
- 额头区域对于记忆和执行功能至关重要,它们的完整性可能会支持衰老中的情绪处理.
- 需要进一步的研究来澄清这些正面连接在积极性偏差和潜在干预中的作用.
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