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Updated: Jun 17, 2026

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长期模拟的微重力会通过Piezo1促进动脉衰老的变化

Jiaxin Zhang1,2, Xinpei Wang1, Zihao Fu1

  • 1Key Laboratory of Aerospace Medicine of Ministry of Education, School of Aerospace Medicine, Fourth Military Medical University, 169 Changlexi Road, Xi'an 710032, China.

Cardiovascular research
|January 25, 2024
PubMed
概括

长期模拟的微重力加速血管衰老,通过增加动脉硬度和纤维化. 这个过程涉及机械传感器Piezo1和microRNA-582-5p,提供潜在的治疗点.

关键词:
冠状动脉硬度 冠状动脉硬度机械拉伸是一种机械拉伸.这是一个微型RNA.微重力是一种微重力.这是一个Piezo1.血管的衰老 血管的衰老

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...