角膜脱光症以外的原交叉链接:一个全面的审查
Grigory A Osipyan1, Husam Khraistin, Mohammad Jourieh
1Department of Corneal Pathology, Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Indian journal of ophthalmology
|January 25, 2024
概括
角膜交叉连接 (CXL) 通过硬化角膜来有效治疗脱落性疾病. 它的应用范围正在扩大,显示出对传染性角膜炎,,甚至是折射错误和玻璃眼的希望.
科学领域:
- 眼科医生 眼科 眼科
- 生物材料科学 生物材料科学
背景情况:
- 角膜交叉链接 (CXL) 于2003年开发,用于治疗角膜脱落性疾病.
- 它是硬化角膜和阻止疾病进展的最有效疗法.
结论:
- 角膜交叉连接是一种多功能治疗方式,在眼科中应用范围越来越广泛.
- 未来的研究可能会将CXL作为各种非眼病的标准治疗方法.
相关概念视频
Fibril-associated Collagen
Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...


