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Allergic Reactions02:06

Allergic Reactions

27.4K
Overview
27.4K
Viral Recombination00:57

Viral Recombination

23.4K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.4K
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

15.1K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
15.1K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.1K
Other Factors Affecting Respiration Centers01:17

Other Factors Affecting Respiration Centers

849
Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical...
849
Exon Recombination02:32

Exon Recombination

3.6K
The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon...
3.6K

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相关实验视频

Updated: Jul 5, 2025

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

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解释SARS-CoV-2喷的情况

Mitch Leslie

    Science (New York, N.Y.)
    |January 25, 2024
    PubMed
    概括

    一种病毒蛋白刺激神经细胞, 表明它可能是未来治疗的目标. 这一发现为治疗神经疾病提供了新的途径.

    科学领域:

    • 神经科学
    • 病毒学
    • 分子生物学

    背景情况:

    • 病毒感染会影响神经功能.
    • 了解病毒与宿主之间的相互作用对于开发治疗至关重要.

    研究的目的:

    • 研究特定病毒蛋白对神经细胞的影响.
    • 确定这种病毒蛋白是否可以作为治疗点.

    主要方法:

    • 使用神经细胞培养.
    • 暴露在病毒蛋白质中的神经细胞.
    • 监测细胞反应和活动.

    主要成果:

    • 发现病毒蛋白刺激神经细胞活动.
    • 观察到神经元信号通路的显著变化.

    结论:

    • 研究的病毒蛋白直接影响神经细胞功能.
    • 这种病毒蛋白代表了新的治疗策略的潜在目标.

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