在前期治疗前,在前列腺癌患者的腹部计算机断层扫描上检测到间歇性肺部异常
Hyun Jin Kim1, Won Gi Jeong, Jeong Yeop Lee
1From the Department of Radiology, Chonnam National University Medical School.
Journal of computer assisted tomography
|January 25, 2024
概括
间歇性肺异常 (ILA) 是前列腺癌患者死亡率的重要预测因素. 在腹部CT扫描上对肺基的常规检查可以帮助为这些患者制定个性化治疗策略.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 前列腺癌和间歇性肺异常 (ILA) 具有共同的风险因素,如年龄和男性性别.
- 在前列腺癌患者中ILA的患病率和影响仍未得到充分研究.
研究的目的:
- 确定前期治疗ILA在接受腹部CT的前列腺癌患者的患病率.
- 评估前期治疗ILA与前列腺癌患者的长期存活率之间的关联.
主要方法:
- 对173名前列腺癌患者的回顾性分析,这些患者在初次泌尿器科诊断后一年内 (2005-2016) 进行了腹部CT.
- 胸部放射科医生在腹部CT上审查了肺部基础,以检测ILA的存在.
- 卡普兰-梅尔分析,日志等级测试,z测试和考克斯回归被用来评估生存和死亡风险因素.
主要成果:
- 在治疗前,ILA在10.4%的患者中被检测出来,在老年人中更常见,目前的吸烟者.
- 治疗前的ILA显着与生存率差 (P < 0.001) 相关.
- 独立的死亡风险因素包括年龄≥70,转移阶段和ILA. ILA是局部性前列腺癌中唯一独立的死亡风险因素.
结论:
- 在前列腺癌患者的腹部CT扫描中,预治疗ILA是一个相当大的发现.
- 前期治疗ILA是前列腺癌患者死亡的独立风险因素.
- 建议前列腺癌患者在腹部CT上进行肺基的例行检查,以告知个性化管理策略.
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