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Updated: Jul 5, 2025

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尿素双酸盐区分糖转移酶超级家族

Leah M Seebald1, Pouya Haratipour2, Michaela R Jacobs2

  • 1Department of Biology and Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|January 25, 2024
PubMed
概括

研究人员开发了新型尿素二酸盐 (UBPs),以抑制参与细菌糖合物合成的糖酶转移酶 (PGTs). 这些UBP揭示了不同PGT超级家族的独特结合机制,为向 prokaryotic 酶的新抗生素开发提供了潜力.

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