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在胎儿右大动脉中增加的肺大动脉间隙:一个匹配的病例对照研究
Bo B Bet1,2, Agnes E van Steijn1, Ingeborg H Linskens2,3
1Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Fetal diagnosis and therapy
|January 25, 2024
概括
在三血管视图 (3VV) 中测量肺大动脉间隙 (PAAo) 和PAAo/AoSVC比率可以帮助诊断胎儿的右大动脉门 (RAA). 一个比率为1.9或更高表明RAA.
科学领域:
- 医疗成像医学成像
- 胎儿心脏病学 胎儿心脏病学
- 产前诊断 在产前诊断
背景情况:
- 在第二季度异常扫描中,右大动脉 (RAA) 的产前检测在三血管视图 (3VV) 中得到了改进.
- 3VV包括肺动脉 (PA),大动脉 (Ao) 和上腔静脉 (SVC).
研究的目的:
- 为了评估测量PA和Ao之间的距离在3VV内的诊断价值,用于检测胎儿RAA.
- 评估PAAo/AoSVC比率在诊断隔离RAA时的有用性.
主要方法:
- 一项病例对照研究包括54名具有隔离RAA的胎儿和162名匹配的对照.
- 在3VV图像上进行了PA-Ao和Ao-SVC距离的测量.
- 计算了肺大动脉间隙 (PAAo) 和PAAo/AoSVC比率.
主要成果:
- 在RAA病例中,平均PAAo距离 (3.1毫米) 比对照组 (1.8毫米) 大得多 (p < 0.001).
- 与对照组 (1.4) 相比,RAA病例 (2.9) 中PAAo/AoSVC比率的平均值显著更高 (p < 0.001).
- 一个PAAo/AoSVC比率切线值为1.9,表明RAA诊断的灵敏度和特异性超过87%.
结论:
- 肺大动脉间隙和PAAo/AoSVC比率在RAA的胎儿中显著增加.
- 升高的PAAo/AoSVC比率 (≥1.9) 是诊断RAA的有价值指标,当观察到增加的肺动脉间隙时.
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