对焦虑和阿片类药物使用障碍的认知行为疗法:开发和试点测试
R Kathryn McHugh1, Garrett M Fitzmaurice1, Victoria R Votaw1
1Division of Alcohol, Drugs and Addiction, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 25 Shuttuck Street, Boston, MA 02115, USA.
Journal of substance use and addiction treatment
|January 25, 2024
概括
针对阿片类药物使用障碍 (OUD) 和焦虑症的新认知行为疗法 (CBT) 协议显示出可行性和可接受性. 虽然焦虑症状有所改善,但CBT协议在这个试点研究中并没有显示出与标准护理相比的优异结果.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 成 药物 药物 药物 药物
背景情况:
- 焦虑障碍经常与阿片类药物使用障碍 (OUD) 一起发生,对治疗结果产生负面影响.
- 为改善患者预后,开发有效的伴随性焦虑和OUD治疗方法至关重要.
研究的目的:
- 开发和试验一种新的认知行为疗法 (CBT) 协议,用于患有同时出现焦虑障碍和OUD的人.
- 评估这个新的CBT协议的可行性,可接受性和初步有效性.
主要方法:
- 以患者和专家反进行代手册开发.
- 在一个开放的试点试验中 (N=5) 测试了12个会话的个人CBT协议.
- 随后,一项随机对照试验 (N=32) 将CBT协议与个人药物咨询进行了比较,所有参与者都接受了OUD的药物治疗.
主要成果:
- 招聘,留住和患者满意度的高率表明了强大的可行性和可接受性.
- 观察到在主体内显著减少焦虑症状严重程度,在3个月的随访中持续.
- 在CBT和对照组之间没有发现焦虑或阿片类药物使用结果的显著差异.
结论:
- 开发的CBT协议是可行和可接受的,用于治疗同时发生的焦虑和OUD.
- 这项试点研究没有显示新型CBT协议在与药物结合时对OUD的现有基于证据的心理社会治疗具有初步优势.
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