卡尔雷素P域衍生"吃我",用于增强树突细胞中的脂质体吸收

Kuo-Ching Mei1, Nagasri Thota2, Pu-Sheng Wei2

  • 1Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 29599, USA; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York, Binghamton, NY 13790, USA.

概括

研究人员使用卡尔雷蒂库林 (CRT) 开发了新型脂质体,以增强细胞药物输送. 这些P域模仿CRT的"吃我"信号,显著提高树突细胞的吸收,没有毒性,提供了一个有前途的仿生方法.

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